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In parallel with basic studies of fibrogenesis he has been involved in applied studies of surrogate markers of fibrogenesis and this has led to the development of algorithms of serum markers that represent an effective means of monitoring fibrosis in individual patients. Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial.

He has attracted grant funding of over .5 million including awards from the MRC, Wellcome Trust and NIH. Clinical Gastroenterology and Hepatology, 15, 1, 96-102.e3.

Well-differentiated hepatocellular neoplasm of uncertain malignant potential: proposal for a new diagnostic category. 10.1016/j.humpath.20 Elsharkawy, A., Schwab, U., Mc Carron, B., Burt, A., Daly, A., Hudson, M.

Efavirenz induced acute liver failure requiring liver transplantation in a slow drug metaboliser. 10.1016/20 Brain, J., Robertson, H., Thompson, E., Humphreys, E., Gardner, A., Booth, T. 10.1111/ajt.12271 Mc Pherson, S., Anstee, Q., Henderson, E., Day, C. 10.1097/MEG.0b013e32835d72cf Robinson, S., Mann, J., Vasilaki, A., Mathers, J., Burt, A., Oakley, F.

He played a pivotal role in establishing the principal cell type involved in fibrogenesis is the hepatic stellate cell and was the first to characterise their cell kinetics in the response to injury establishing that there is not only proliferation of these cells in response to necrosis but a phenotypic modulation to myofibroblast-like cell.

In August 2014 he became acting Executive Dean of the Faculty of Health Sciences and was appointed to the substantive role in December 2014. Professor Burt has a long standing interest in the pathogenesis of liver fibrosis. Inflammation-induced Ig A cells dismantle anti-liver cancer immunity. 10.1038/nature24302 Mc Pherson, S., Wilkinson, N., Tiniakos, D., Wilkinson, J., Burt, A., Mc Coll, E. This is an important part of progressive liver disease and an essential component for the development of cirrhosis. In 1985-86 he spent time in the lab for cell biology and histology at Free University of Brussels under the direction of Professor Eddie Wisse. Sulfatase-2: A prognostic biomarker and candidate therapeutic target in patients with pancreatic ductal adenocarcinoma. 10.1038/bjc.2016.264 Liew, V., Chapman, M., Nguyen, N., Cousins, C., Plummer, M., Chapple, L. On return to the UK and on completion of his postgraduate training in Surgical Pathology he moved to the University of Newcastle upon Tyne to become Senior Lecturer in Pathology and Honorary consultant Histopathologist.




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